SHOX2 anticorps (Middle Region)

N° du produit ABIN1109006

L’anticorps Lapin Polyclonal anti-SHOX2 a été validé pour WB. Il convient pour détecter SHOX2 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour SHOX2 anticorps (Middle Region) (ABIN1109006)

Antigène: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHOX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SHOX2 anticorps

Épitope: Middle Region

Séquence: SEARVQVWFQ NRRAKCRKQE NQLHKGVLIG AASQFEACRV APYVNVGALR

Réactivité croisée (Details): Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: The immunogen for anti-SHOX2 antibody: synthetic peptide directed towards the middle region of human SHOX2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur SHOX2

Antigène: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Autre désignation: SHOX2 / SHOT

Sujet: SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.Synonyms: Homeobox protein Og12X, OG12X, Paired-related homeobox protein SHOT, Short stature homeobox protein 2

ID gène: 6474

NCBI Accession: NP_006875

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development